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As with all GLP-1 receptor agonists and incretin-based therapies, the most commonly reported adverse effects in the Phase 2 trial were gastrointestinal in nature

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Semaglutide: Also effective, with many users losing 1015% or more of their body weight

TRANSCEND-T2D-1 Diabetes Trial TRANSCEND-T2D-1 was the first Phase 3 readout in type 2 diabetes, reported in March 2026 [8]

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