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There was an increased number of thyroid cancers in the Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER) clinical trial evaluating liraglutide versus placebo, but the risk did not reach statistical significance (hazard ratio [HR] 1.66, 95% CI 0.406.95), as well as in a meta-analysis of 12 other clinical trials with liraglutide (odds ratio [OR] 1.54, 95% CI 0.406.02) (7,8)

Hold needle in place for 5-10 seconds after fully depressed 6

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Total time: 5-7 minutes including preparation and hold time

Recent advances in clinical practice challenges and opportunities in the management of obesity