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NLRP3 activation further appears to be inhibited by the activity of the ketone body HB produced by the KD, suggesting that the modulation of neuroinflammation contributes to KD efficacy (Youm et al., 2015)

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It is clinically established iron chelator binds excess free iron, thereby reducing its availability for the Fenton reaction and subsequent ROS generation

[273] For example, during the early 1970s in the United States, amphetamine became a schedule II controlled substance under the Controlled Substances Act