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S-Adenosyl methionine quantification assay Intracellular SAM levels were quantified with Bridge-It S-Adenosyl Methionine (SAM) Fluorescence Assay (#1-1-1003, Mediomics)

Rotenone and RSL3 treatment Rotenone (HY-B1756, MedChemExpress) was dissolved in DMSO and then diluted in M2 medium to final concentrations of 1, 2, and 4 M 65

Vitamin C may indirectly assist in minimizing oxidative stress associated with chronic stress by maintaining adrenal health and normalizing cortisol levels (100)

(3) Increased skin thickness, firmness, and elasticity A 12-week trial with 71 women showed that GHK-Cu increased skin firmness, improved clarity, and reduced fine lines

10.1038/nchembio.83 44 DikicI.ElazarZ

The advantages of oral glutathione supplements include tolerability, affordability, and convenience