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Several antiretroviral drugs, such as Nelfinavir, Efavirenz, and Zidovudine, have been implicated in stimulation of inflammatory responses, including leukocyte adhesion, in a process linked to elevated oxidative stress (Mondal et al

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Patch test 24 hours prior to full application to assess sensitivity

Furthermore, in the gastrocnemius muscle of SOD1 G93A mice, the activities of the TCA cycle enzyme 2-oxoglutarate dehydrogenase (OGDH) were found to be reduced in the late symptomatic phases of the disease, indicating impairments in the TCA cycle pathway (Tefera et al., 2016)