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In response to repetitive highfrequency steps of the stimulus, inhibition removal may be too slow, and hence, activity would not be observed in response to all repetitive stimulations, a phenomenon known as periodic skipping (compare Appendix Fig S1B and C and see also experimental evidence in Larsch et al , 2015

Vitamin C plays a crucial role in collagen production , which gives skin its firmness and elasticity

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Consider: daily multivitamin, vitamin D 2,000-4,000 IU daily (most people are deficient), vitamin B12 if energy is low, calcium 1,000-1,200mg daily (especially for women), fiber supplement if constipated, protein powder if struggling to hit 80-100g daily from food

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Claudin-5: gatekeeper of neurological function