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ROS can induce AP-1, a heterodimer composed of c-fos and c-jun, which downregulates type I collagen and upregulates MMPs in aging skin [77], and can also inhibit the TGF- signaling pathway in skin fibroblasts

doi: 10.1016/j.rmed.2016.10.014 7 ChalmersJDAlibertiSPolverinoEVendrellMCrichtonMLoebingerMet al

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A 2023 study found that the antioxidant effects of silymarin can stimulate anti-tumor activities as well as protect healthy cells from damage induced by chemotherapy

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