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Therefore, optimal protection against such injury may necessitate the antagonizing of both pathways

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doi: 10.1038/nrneurol.2012.263 139 LocatelliG.WortgeS.BuchT.IngoldB.FrommerF.SobottkaB.et al

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This extraordinary potency difference stems from Dihexas mechanism as an HGF mimetic binding to c-Met receptors, which triggers intracellular signaling cascades distinct from BDNFs TrkB receptor pathway

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