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They work a step higher up the chain, mimicking the body's own GHRH to signal the pituitary

Plasmids of wildtype and mutants of ARE motifs were transfected to K562 (#CRL-3344, ATCC), an erythroleukemia cell, along with pDsRed1-N1 (PT3405, Clontech), which is used as a transfection efficacy control

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They have read that peptides can replace hormone replacement therapy, or they assume any peptide will fix any hormone problem

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[3] [4] The role of GIP receptor activation is not fully understood