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Additionally, in vivo pharmacokinetic (PK) parameters were evaluated to determine oral bioavailability, and pharmacodynamics were evaluated to determine the glucose-lowering effects in diabetic db/db mice

Missed doses

101 I.v

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The publication reported the estimated mean percent change in body weight from baseline to week 68 for each arm, with the combination arm showing a substantially larger estimated reduction than placebo, and the cagrilintide-alone arm showing an intermediate reduction