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Increasing the serum persistence of an IgG fragment by random mutagenesis

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GLP-1 medications (like Semaglutide, Tirzepatide, and Liraglutide) help regulate blood sugar and reduce appetite, leading to effective and sustained weight loss

Consistent with this idea, expression of aldose reductase in the mouse liver causes the same redox change in the absence of diabetes, which leads to fatty liver ,as shown recently 22

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