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Notably, GLP-1-producing neurons within the nucleus tractus solitarius (NTS) project axons to the VTA and other limbic structures, further embedding GLP-1 signaling within neural networks that regulate reward and motivation (Llewellyn-Smith et al., 2011

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340 Tri-Agonist for GLP-1R, GIPR and GCGR Recently, a triple agonist for GLP-1R, GIPR and GCGR was developed and tested on diet-induced obese mice

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