In recent weeks, Novo Nordisk's commercial team increasingly pressured us to control clinical standards and steer patients to Wegovy regardless of whether it was clinically best for patients," Hims & Hers CEO Andrew Dedum wrote in a statement posted on X
Further, although incompletely described, multiple studies are available to provide insights into the mechanistic underpinnings, which appear to be associated mostly with indirect cardioprotective benefits owing to the ability of GLP-1 RAs to address hyperglycaemia, and reduce body weight, and, amongst others, inflammation
Synthetic FXR agonist GW4064 prevents Diet-Induced hepatic steatosis and insulin resistance
Current GLP-1 use by age is reported in KFF's writeup of the poll
There are currently no legal generic versions
107 However, the response occurs after the cephalic phase of insulin secretion implying that any neuronal signals that promote insulin release do not induce GLP-1 secretion