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Ask the doctor: B12 shots vs
Clinically, kisspeptin is very well tolerated and can reinitiate pulsatile LH secretion in women with hypothalamic amenorrhea, so it will be applicable where low GnRH drive is the underlying cause
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The model suggests that the lack of vitamin B 12 GSH correlation is explained by suppression of activity in the trans-sulfuration pathway that limits the synthesis of cysteine and GSH from homocysteine
Circadian Rhythm Regulation: Normalizes sleep-wake cycles in animal models [Graf 1981]
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