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Musculoskeletal toxicities usually include myalgias, arthralgias with elevated muscle enzymes signifying significant muscle destruction [26, 27]

The tab for the entire build came to $140,000, a sum equivalent to around $2.5 million in todays money

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It should answer practical questions about care quality, follow-up, and safety

Regardless of the specific contract that gets negotiated, the goal should be to help patients who need access, expand the market for manufacturers and address Medicares concerns about how these drugs will perform long-term

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