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The classical complement cascade mediates CNS synapse elimination

Research-grade 5-Amino-1MQ products are intended strictly for laboratory research use only and are not approved for human consumption

Samples were quenched with 10mM EDTA, pH 8, and buffer exchanged into 20mM HEPES, pH 8, 200mM NaCl, 1mM DTT to remove excess fluorescent peptide, passed over Ni-NTA resin to remove sortase, and then subjected to SEC

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62 RGT075 RGT075 is a small oral GLP-1RA identified through Computer-Accelerated Rational Design (CARD) with potent G-protein-coupled cAMP signaling