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The patients in the age group of 2540 years were randomised into L-carnitine (1000 mg oral dose), N-acetylcysteine (oral dose), and placebo (sugar sachets) treatments

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Moving from 2.5 mg to 5 mg to 7.5 mg too quickly does not give the body time to adapt

Edwards N, Saltman RB

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Finally, in some included studies, the primary outcome was not aiming at the weight change after treatment withdrawal, so the information was incomplete