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Viral constructs The Cre-inducible adeno-associated virus (AAVs) were purchased from addgene Watertown, MA USA)

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Beyond their insulinotropic effects, GLP-1R and GIPR signaling also influences lipid metabolism by modulating hepatic lipid handling and adipose tissue function

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For example, selenium is required for the activity of glutathione peroxidases, which are scavengers of hydrogen peroxide in subcellular compartments