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Similarly, Section 503B does not allow for compounding of drugs that are essentially a copy of one or more approved drugs but the statute notes that this does not apply to drugs on the drug shortage list in effect under Section 506E. The 506E shortage list recognizes drugs that have low availability due to manufacturing or quality problems, delays or discontinuations

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This allows compound 2 to execute positive allosteric modulation through enhancement of both agonist binding and G protein coupling

2009 Jan 27;338:b277