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A doctor will usually recommend urinating at one-hour intervals and gradually increasing the intervals between urination over time
doi: 10.1532/hsf.2193
The formula is: Daily sublingual dose = (Weekly injectable dose x Injectable bioavailability) / (7 days x Sublingual bioavailability) Using 80% injectable and 30% sublingual bioavailability as the midpoint estimate: Daily sublingual = (Weekly injectable x 0.80) / (7 x 0.30) = Weekly injectable x 0.38 This means a 10 mg weekly injectable dose translates to approximately 3.8 mg daily sublingual
The answer depends on whether you're asking about a single schedule adjustment (safe within limits) or a pattern of early dosing (creates cumulative risk)
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Endocrine Reviews, 24(4), 488-522
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