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Coffee : The caffeine may improve alertness, but it can also mask drowsiness, giving you a false sense of sobriety

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Hormonal Feedback Loops : Disrupted sleep also dysregulates ghrelin (the hunger hormone) and leptin (the satiety hormone), potentially undermining metabolic goals

Losing even a small amount of weight can relieve pressure on the LES and reduce acid reflux episodes

However, emerging evidence suggests a potential link between GLP-1 therapy and altered pain perception, possibly through several mechanisms: 1- Neuroinflammation and Microglial Activation: GLP-1 receptors are expressed in the brainstem, spinal cord, and dorsal root ganglia, regions involved in pain modulation