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The search included studies with results available up to June 10, 2025, and was restricted to completed trial records and full-text articles available in English

Effects of liraglutide on visceral and ectopic fat in adults with overweight and obesity at high cardiovascular risk: A randomised, double-blind, placebo-controlled, clinical trial

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This modulation occurs by regulating the spinal dorsal horn microglial pathway through GLP-1R activation, leading to alterations in spinal excitatory synaptic transmission under neuropathic pain conditions 13,14,15,16,17,18