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There is also a theoretical risk that excessive antioxidants could interfere with the body's natural ability to signal for repair

This therapy should not be used during pregnancy or while breastfeeding

16 and Supplementary Figs

We should watch for unusual skin changes

(Native, unmodified recombinant human IGF-1, sold as mecasermin/Increlex, is FDA-approved only for a narrow pediatric growth-failure indication and is chemically distinct from the LR3 analog.) In the US it is manufactured and sold almost exclusively as an unregulated "research chemical" labeled "not for human consumption," a labeling practice peptide vendors use to avoid marketing it as an unapproved drug