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However, it has remained unclear whether GH induces cell expansion directly through GHRs expressed on these cells, or indirectly via stimulation of secondary growth factors produced by granulosa cells, such as IGF, which would then directly act on theca cells (32, 33)

Missing doses or varying injection timing by multiple days can reduce semaglutide's appetite-suppressing effect and increase rebound hunger during the gap

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However, they were instructed to eat more if they were losing weight