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Inflammation can shorten the hair growth cycle and trigger telogen effluvium (excessive shedding)

As of mid-2026, three trials have reported results

In contrast to other lcFAODs, congenital malformations, such as dysmorphic features, renal cysts, intracerebral and intrahepatic calcifications have been reported in several cases that suffered from the lethal neonatal form [107,108,109,110]

3 These outcomes often invite comparison with GLP-1 treatments, raising questions around sermorelin vs semaglutide weight loss efficacy