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In humans, intravenous administration of metformin results in rapid renal elimination, with little or no metformin detectable in the faeces [10], consistent with negligible biliary or GI secretion of metformin

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Comp Clin Pathol 28 , 17511759 (2019)

Overpatented, overpriced: How excessive pharmaceutical patenting is extending monopolies and driving up drug prices

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(A) Risk of bias summary: review authors judgments about each risk of bias item for each included study