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Activation of the Transcription Factor NRF2 by Polyphenols, Vitamins, and Selenium The nuclear factor erythroid 2-related factor 2 (NRF2) responds to the OS by binding to the regions of genes that control the antioxidant response (ARE), and the NRF2/ARE induction pathway is of great interest due to its activation by phytochemical compounds [147]

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

the toxic load is increased by 10%

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Moreover, another prospective study indicated that having a mother or maternal relatives with lung cancer is a risk factor for the disease [41]