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In addition, valproate can cause decreased IQ scores and neurodevelopmental disorders following in utero exposure

At the end of the study, the rats were under anesthesia with ketamine (10 %)/ xylazine (2 %) mixture (80/5 mg/kg) (Alfasan, Netherland), and 5 ml blood was collected by cardiac puncture

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Given the potential risks associated with semaglutide, such as its effects on gallbladder dysfunction and diabetic retinopathy, how should clinicians balance these risks against its demonstrated benefits in managing obesity and Type 2 diabetes