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Newmark J, Romano JA Jr (2018): Chemical Terrorism (Chapter S3)

Given its essential role in skin biology, GHK-Cu is widely used as an anti-aging and reparative ingredient in cosmetics

Collectively, these recent contributions argue that future GSH-centric redox sensing and nanomedical approaches should (i) incorporate organelle targeting (especially mitochondria) to exploit subcellular redox heterogeneity, (ii) embed analyte-responsive activation into both therapeutic and imaging components, (iii) combine biochemical sensing with optical or thermal engineering for spatiotemporal control, and (iv) favor clinically translatable carriers (e.g., PLGA) for delivery

Sweetman SC, editor

Timeline depends on your skin type, absorption rate, and daily sun exposure

29 , e70406 (2025)