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In addition to data quality, in our experience one limitation comes from the inherent bias within healthcare data sets

Patients (or front-desk staff) confirm current diabetes medications at every check-in, populating a structured field in the record rather than leaving the question to the encounter narrative

Association of semaglutide with tobacco use disorder in patients with type 2 diabetes: target trial emulation using real-world data

Compounded versions of GLP-1 receptor agonists are not FDA-approved and can increase the risk of contamination when purchased from unreliable sources

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