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TLR4 expression is increased in patients with GERD, triggering an inflammatory response involved in the further development of GERD.TLR4 expression in normal squamous epithelial samples is mainly confined to the basal layer of the squamous epithelium, which routinely may not come into contact with PAMPs expressed by the esophageal microbiota, and reflux increases TLR4 expression (49)

Glutathione S-transferases deletions may act as prognosis and therapeutic markers in breast cancer

Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer

Quantification was performed using calibration curves and the identification was done with a custom database

Standard L-Carnitine is the basic form found naturally in muscle tissue and is the version most commonly used in sports nutrition supplements

Below, we briefly describe these components and provide details for aspects of the study not reported elsewhere (17)