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Despite setbacks in biodistribution, toxicity, and scale-up manufacturing challenges, ongoing research is still optimizing nanoparticle design for targeting specificity and clinical applicability [110]

After receiving a vaccination, some individuals might experience arm soreness

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For histological analysis, the femoral and tibial condyles were fixed in 10% neutral buffered formalin, decalcified with 20% EDTA, embedded in paraffin, and sectioned into 5-m thick frontal slices