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With the introduction of the mutant KRAS gene, insulin regained the ability to induce invasion and proliferation in pancreatic ductal cells (Wang et al., 2019)

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385 Astrocytic overload with mercury causes cell swelling, it severally impairs glutamate uptake, K + buffering and glutathione production, 386 this causing secondary excitotoxicity and oxidative damage to neurones

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the root drivers need to be identified through a thorough history and relevant laboratory testing before selecting interventions

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