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Study Objectives

Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients

Storage & Sustainability

A transcriptional regulator of atrogin-1 and MuRF1 has been shown to be nuclear factor-kB (NF-kB), an induced transcription factor

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1 Consequently, while multi-receptor agonists represent a promising future direction in obesity pharmacotherapy, their application in adolescents must be interpreted cautiously, with careful consideration of developmental safety, long-term outcomes, and ethical implications of extrapolating adult data to younger populations