retatrutide phase 2 nejm weight loss 48 weeks Trial of for Obesity VisualAbstract: Retatrutide reduces body weight

Restarting at a lower dose and re-titrating up over several weeks is the safer approach

But they are also common, medically explainable and not a sign that something is wrong

If you decide to move forward with a GLP-1 drug and youre not on any other medication, you can get started at any time

If youre considering starting a GLP-1 medication, heres what you need to know before you begin

Most GLP-1 agonists do not require dose adjustment for mild to moderate renal impairment, though specific agents have varying recommendations for severe impairment

For flights longer than 4 to 6 hours, consider using two gel packs and swapping them if one warms up