Treatment usually begins with a lower dose to help your body adjust comfortably
Whilst injectable GLP-1 therapies such as semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda) are well established in UK clinical practice, transdermal patch formulations represent an emerging area of pharmaceutical development
Theyre simply too big to get through the skin barrier, which is designed to keep larger substances out
Heat may affect the patchs performance
However, as of now, the FDA has approved GLP-1 drugs only in the form of injections and pills 1 , 2 , and there are no approved form of GLP-1 transdermal (skin) patches which are in medical use
Research shows that peptides like semaglutide cannot pass through the skin in enough amounts to work