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Old concerns about hormone therapy have been debunked by new research, especially when treatment is started early and monitored by an experienced provider

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Slow-transit constipation symptoms may include infrequent bowel movements, bloating, and abdominal discomfort (Jamshed 2011

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This was also accompanied by reduced activity of acetylcholinesterase, increased activity of antioxidant enzymes (SOD and CAT), and downregulation of the expression of A and APP (66)