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Specific inhibition of Sirt2 suppressed the apoptotic phenomenon and increased number of insoluble S positive inclusions (Outeiro et al., 2007

The 2011 discovery cohort was sampled years prior to initial proteomics experimentation, however the sample size ( n = 60) was sufficient to detect moderate to large differences between groups

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Mitochondrial superoxide decreases yeast survival in stationary phase

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