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IGF-1 LR3 carries an arginine substitution at position 3 and an N-terminal 13-amino-acid extension that reduces IGFBP affinity by roughly 1,000-fold, extending its active window to 20-30 hours

[82] Hypothetical cellular organisms with self-replicating RNA but without DNA are called ribocytes (or ribocells)

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4, June 2011, pp