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F., Myung, S

Its efficacy was confirmed by a meta-analysis published recently in the Mayo Clinic Proceedings

Earlier phase research published in the New England Journal of Medicine found doubledigit mean weight loss at the highest doses in adults without diabetes, but clinicians say headtohead trials and insurance coverage decisions will ultimately shape who can access the drug after any approval

On/off cycling here is driven by caution, not by tolerance data: because there is no long-term human safety record, building in scheduled off periods is the conservative research default

Expected timeline: Faster onset than topical-only

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