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Upregulation of MDR1 and induction of doxorubicin resistance by synergistic use of histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

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Antioxidant enzyme activity 20, 40, 60, and 90 mM salt treatments significantly (p 0.001) increased SOD activity by 10%, 19%,42%, and 49%, CAT activity by 11%, 15%, 33%, and 34%, APX activity by 27%, 60%, 73%, and 74%, GPX activity by 31%, 44%, 66% and 72%, respectively, relative to with respect to those in untreated Mentha piperita plants (Fig

J., Anawalt, B

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M., Swalm, B