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The risk of yo-yo effects, where patients lose muscle on the drug and regain fat after stopping, is a real concern

Current evidence generally supports that these medications can be effective after bariatric procedures, though more research is needed on their long-term outcomes in post-bariatric populations

doi: 10.1016/j.amjmed.2024.04.032 113 MarfellaRPrattichizzoFSarduCRambaldiPFFumagalliCMarfellaLVet al

However, the short half-life of these drugs is a major limitation to treatment and prolonged usage can also lead to adverse effects, such as depression, reduced breast size, and vaginal dryness 16, 17

Kulkantrakorn K, Lorsuwansiri C, Meesawatsom P

Or do you think it would be more likely for him to organize a committee to discuss communications