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However, the levels of carnitine in the muscles may only go up slightly, due to abnormal OCTN2 which affects the uptake of carnitine into muscle cells

nytimes.com/2023/05/16/well/live/ozempic-alternatives-semaglutide.html Blum D

[13] [14] It is worth noting that while acne is not a recognised side effect, the Saxenda SmPC does list other skin reactions including rash, urticaria and injection-site reactions as known adverse effects

The primary outcome of this study was the first diagnosis of CRC within 15 years from the initial treatment of GLP-1RAs or non-GLP-1RA diabetes medications (insulin, metformin, alpha-glucosidase inhibitors, dipeptidyl-peptidase-4 inhibitors (DPP-4i), sodium-glucose cotransporter-2 inhibitors (SGLT2i), sulfonylureas (SU), and thiazolidinediones (TZD))

The mechanism of action of these drugs, in simple terms, is that they mimic natural gut hormones (such as GLP-1, and in the case of tirzepatide, also GIP) which regulate appetite and satiety