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These compounds contain a single-ringed nitrogenous base that pairs with a purine nucleotide counterpart

In addition, Nrf2 can also regulate the expression of downstream enzymes such as GST and GR, further improving the cell's antioxidant defense network and enabling cells to more effectively respond to damage caused by oxidative stress

So, helminths intervene from the first events in immune recognition to favour the development of a regulatory environment in which host and parasite can remain in a long-term homeostatic relationship

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10.1016/j.sjbs.2017.11.051 188

Gimenez J, Nunes CD, Vaz PD, Valente AA, Ferreira P, Calhorda MJ