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The authors compile data showing GHK-Cu modulates expression of more than 4,000 human genes including substantial upregulation of antioxidant defense genes, DNA repair genes, and genes encoding collagen and elastin biosynthesis enzymes while downregulating pro-inflammatory and tissue-degradation pathways
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Cells stained blue under an optical microscope were counted as positive cells, and DAPI counterstain was used to count the total cell number
Cell Death Differ 23:270278 Hensley CT, DeBerardinis RJ (2015) In vivo analysis of lung cancer metabolism: nothing like the real thing
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