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Think of blood tests like a report card for your health
The full effect can take 12 weeks or longer, depending upon how well you tolerate the medicine
[234] [200] In addition to presynaptic actions that regulate DAT, TAAR1 activation exerts a somatodendritic inhibitory influence on midbrain dopamine neurons by reducing their firing rate via G protein-coupled inwardly-rectifying potassium channels, an effect that is expected to reduce action potential-dependent (vesicular) dopamine release into the synaptic cleft
By switching to a once-daily, modified-release formulation, Pfizer aims to reduce side effects and improve patient compliance
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Diabetes Care , 40 (9), 1218-1225
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