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Hernandez NS, Schmidt HD
GLP-1 receptors are expressed in brain regions involved in reward processing and food motivation, including the nucleus accumbens and ventral tegmental area
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Growth and apoptosis Ex-4 significantly improves the survival of rat cortical neurons under oxygen/glucose deprivation (OGD) conditions through reduced apoptosis rates, increased expression of glucose-regulated protein 78, and decreased levels of C/EBP-homologous protein, indicating the role of Ex-4 in modulating unfolded protein response for protecting neurons from ischemic damage [56]
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doi: 10.1038/nm1168 65 ElsonAETDotsonCDEganJMMungerSD
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