Millions of red blood cells are being made and dying off daily and the body builds up stores within the body, specifically the bone marrow
If your doctor feels you're a good candidate for vitamin B12 injections, they'll give you a prescription for a certain dosage
The most common reasons are inadequate dosing discipline (inconsistent injection timing, missed doses), improper storage leading to peptide degradation, dosing during non-fasted states where AMPK activation is blunted, or lack of structured caloric deficit and training stimulus
Lidocaine local anesthetic used to decrease the pain associated with intramuscular injection
You take certain medications: Long-term use of proton pump inhibitors (for acid reflux) or metformin (for diabetes) can interfere with B12 absorption
These skin reactions typically resolve upon discontinuation of high-dose supplementation