Koksal et al
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Plasma levels of GHK have been observed to decline with age
SCFAsacetate, propionate, butyrate, produced by fibre-fermenting taxa (e.g., Faecalibacterium , Roseburia , Anaerostipes ), activate FFAR2/3 on enteroendocrine L cells, stimulate GLP-1 and PYY secretion, and upregulate intestinal expression of both TGR5 and FXR, thereby increasing sensitivity to secondary bile acid signaling [157,158]
Scientific Background Small-molecule metabolic regulators are widely used in research exploring enzymatic signaling pathways
Blood was collected in EDTA-coated microvette tubes, chilled on ice and centrifuged at 3,000 g and 4 C for 10 min