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Executive Summary 3.1

Mol Cell Biochem (2020) 467:112

Nutrients , 13(10), p.3432

Clinical evidence: in a cohort study involving 4,125 elderly individuals, higher cereal-derived RS intake (15 g/day) was associated with a 28% reduction in serum IL-6 levels and a 35% reduction in TNF- levels compared to low-RS intake ( 90%sufficient to meet 25% of daily protein requirements and support tryptophan (serotonin precursor) and tyrosine (dopamine precursor) supply (304)

Integrating behavioral counseling and psychological monitoring for instance through motivational interviewing, cognitive-behavioral strategies, or digital adherence tools could enhance both pharmacologic and lifestyle outcomes